Dental stem cells can produce cells which produce milk


The ability of adult stem cells to produce various tissue specific populations of cells is of significant importance in the fields of medical and dental science. These cells can replace weakened cells, and are thus a good alternative to traditional tissue regeneration medical therapies. This could also cause whole tissues and organs to develop de novo in the future.

Both epithelial cell types of the teeth may be created by dental epithelial stem cells; but it was not yet clear if these cells could also create non-dental cell populations.

Researchers in The University of Adelaide brought a new hope for stroke patients since they have discovered that stem cells taken from teeth can grow to resemble brain cells, suggesting they could one day be used in the brain as a therapy for stroke.

The researchers used advanced genetic, molecular and imaging techniques to allow effective tracking of transplanted dental stem cells in the animals' mammary gland fat mat. The findings indicate that the dental stem cells contribute to the development of the mammary gland and are capable of creating both mammalian cell populations and, even more strikingly, milk production cells.

Ectodermal appendages such as hairs, teeth and mammary glands are highly specialized structures that develop through continuous molecular crosstalk between epithelium and mesenchyme. These organs exhibit morphological and regulatory similarities during the earliest stages of development

Recently, genetic lineage mapping studies have identified different epithelial stem cell communities in organs such as skin, mammary glands, and teeth. Multipotent dental epithelial stem cells (DESCs) which express stem cell markers such as Gli1, Bmi1, and Sox2 are located at their rear end, the so-called cervical loop epithelium, in the continuously erupting rodent incisors.

JDRP is an open access peer review journal who publishes different types of articles related to the field of dental or tooth problems, its cure, diagnosis and treatment. People who are interested in submitting their article can go through the URL link